Recently, it has been shown that the Mitochondrial aldehyde dehydrogenase is responsible for the bioactivation of nitroglycerin prior to the release of NO, which is a strong vasodilator.
近来,有研究表明线粒体乙醛脱氢酶是体内硝酸甘油生物转
的主要途径,线粒体乙醛脱氢酶同时具有脱氢酶和酯酶的
性,其酯酶
性可以通过将硝酸甘油脱硝形成一氧
氮,进而
扩张。