" It's a first-rate institution for hopeless cases."

“对于那些无可救药的人来，那是家第一流的机构。”

And no matter what I do, no matter how hopeless I am...

不管我做什么，不管我多绝望。

“Goodness. I expect I was hopeless, was I? ”

“天哪，我还以为自己不会有多大出息呢！”

Populist demagogues eventually lose power because they are hopeless at governing.

民粹主义的煽动者们最终下台，因为他们治理无能。

It felt like the most hopeless moment.

这感觉就像是最绝望的时刻。

This is hopeless. - Have a little faith.

我绝望了 -有点信心。

At times, the task looks truly hopeless.

有时这个愿望看起来根本不可能实现。

To his parents, the situation seemed hopeless.

对他的父母来，这种情况似乎没有希望治好。

" Oh Bertha's hopeless, all right, " said Percy.

" 唉，伯莎这个人确实让人很伤脑筋。" 西。

" You're hopeless, Lenina, I give you up."

“列宁娜，你简直无可救药，我拿你没有办法。”

It was hopeless to ask any more questions.

再继续问下去也是无望的了。

Ove wasn't hopeless, in his own view.

欧维其实并不认为自己无可救药。

Hopeless? Like your entire life has no meaning?

绝望吗？像是这一辈子都毫无意义了吗？

I'm sorry, Cooper, their case is hopeless.

我很抱歉，Cooper，他们的确毫无希望。

It's hopeless when you tell them off.

训斥她们时更是没招。

This person might feel lost, feel hopeless, feel lonely.

这个人可能会感到失落，感到绝望，感到孤独。

When she was at school, she was really hopeless.

她上学的时候，觉得自己完全没有希望。

Five years ago we felt hopeless.

五年前，我们感到绝望。

The movie makes communication with the locals seem hopeless.

这部电影将与当地人的交流显得毫无希望。

Were it so, your case would indeed be hopeless.

如果是这样，你的情况确实没有希望了。