Mr. Sabanayagam studies the epigenome as it relates to microgravity.

Sabanayagam研究了微重力下的表组基因组。

After about a week the scientists take out the worms. They look for changes in the worms' epigenome.

一周后科学家将蠕虫取出，然后观察蠕虫表观基因组的改变。

The epigenome is kinda like Play-Doh on the genome.

表观基因组有点像基因组上的橡皮泥。

And that epigenome is constantly changing.

表观基因组是不断变化的。

The epigenome also mediates a lifelong dialogue between genes and the environment.

表观基因组同介导终生对话在基因环境中。

As twins get older, their epigenomes diverge, affecting the way they age and their susceptibility to disease.

当双胞胎慢慢，的表观基因组不一了，影响了的寿命受疾病的损害程度。

The set of all of the chemical tags that are attached to the genome of a given cell is called the epigenome.

所有的化学标记都依附于染色体组，属于一个特定的细胞被称作是表观基因组。

Think about developing therapies that target the epigenome.

想想开发靶向表观基因组的疗法。

The epigenome can be changed by the environment. And those changes pass from one generation of worms to the next.

表观基因组可以被环境改变，这些改变从一代蠕虫传递到下一代。

But in addition to the primary sequence of DNA, in addition to the As, Ts, Cs, and Gs, there's our epigenome.

但是除了 DNA 的初始序列，除了 A，T，C G，还有我的表观基因组。

A balanced lifestyle that includes a healthy diet, exercise, and avoiding exposure to contaminants may in the long run create a healthy epigenome.

一个平衡的生活方式包括健康的饮食，锻炼，避免暴露于污染从远来看，能够创造一个健康的表观基因组。

Your mother's or your father's experiences as a child, or choices as adults, could actually shape your own epigenome.

你的母亲或者父亲作为孩子的经历，或者成为成年人后的选择，事实上可能形成了你自己的表观基因组。

So they're essentially using Evo 2 to write messages in the language of the epigenome.

所以基本上是使用Evo 2用表观基因组的语言来写信息。

Each of the approximately 200 cell types in your body has essentially the same genome but its own distinct epigenome.

约有200细胞类型在你的身体里，每一个细胞类型都有相同的染色体组但是拥有自己不同的表观基因组。

You mentioned that Evo2 can be used to control the epigenome, that layer of control on top of DNA that influences gene expression.

你提到Evo2可以用来控制表观基因组，即DNA之上的一层控制层，影响基因表达。

Right. But before we get too carried away with the possibilities, I want to touch upon something we discussed earlier: the epigenome.

对。但在我被这些可能性冲昏头脑之前，我想谈谈我之前讨论过的事情：表观基因组。

From its ability to predict mutations and generate new DNA sequences, to its potential for controlling the epigenome and even designing entire organisms.

从其预测突变生成新的DNA序列的能力，到其控制表观基因组甚至设计整个生物体的潜力。

So when we're young, our epigenome is pristine, it's set with genes on and genes that  are off that maintain a cell's identity.

所以当我年轻的时候，我的表观基因组是原始的，由维持细胞特性的基因关闭基因组成。

Precisely. They demonstrated the effectiveness of this technique in a remarkably creative way. They actually programmed Evo2 to write simple Morse code messages into the epigenome.

正是如此。以一种非常有创意的方式证明了这项技术的有效性。实际上对Evo2进行了编程，使其能够将简单的摩尔斯电码信息写入表观基因组。