Ankylosing spondylitis, also called Bechterew disease, is part of a group of diseases called seronegative spondyloarthropathies.

强直性脊柱也称Bechterew病，是一类旧称为“血清阴性脊柱病”疾病中一种。

In ankylosing spondylitis there's chronic inflammation of the intervertebral joints and the facet joints of the spine.

患有强直性脊柱时，椎间盘和突存在症。

Inflammation and pain from ankylosing spondylitis is usually treated with non-steroidal anti-inflammatory drugs like ibuprofen.

强直性脊柱症和疼痛通常采用如布洛芬等非甾体类抗药来治疗。

Ankylosing spondylitis is a systemic inflammatory disease, so it can cause symptoms, like weight loss, fevers, and fatigue.

强直性脊柱是一种全身性症性疾病，因此能够引起全身症状，如体重减轻、发热和疲劳。

Ankylosing spondylitis can be diagnosed using MRI, where there's typically erosion and narrowing of the joint spaces early on, and joint fusion later on.

利用MRI可诊断强直性脊柱，病程早期通常可见腔侵蚀和狭窄，晚期可见融合。

Most individuals with ankylosing spondylitis have the gene HLA-B27, which is a gene that encodes for a specific type of MHC class I molecule.

许多强直性脊柱患者都携带HLA-B27基因，该基因能编码一种特定MHC Ⅰ类分子。

So ankylosing spondylitis is a chronic inflammatory disease that affects the vertebral joints and makes the spine really stiff, but can also cause inflammation in other parts of the body like the eyes and blood vessels.

因此，强直性脊柱是一种累及脊柱并使脊柱变得僵直慢性症性疾病；它也会累及身体其他部位，如眼部和血管。