At high magnification, the germinal center in this reactive lymph node follicle has prominent macrophages with irregular cellular debris (so-called "tingible body macrophages").
When follicular mucinosis occurs in lesions of mycosis fungoides, affected areas on the scalp or beard may present with sharply circumscribed plaques of alopecia.
Then their synthese speed slows down.But the synthese of RNA and DNA inthe follicular cell is continuous during vitellogenesis, which may relate toformation of livetin.
Meanwhile, the primordial follicle turns into a primary follicle, meaning that the follicular cells that surrounding the primary oocyte develop into granulosa cells.
Once puberty hits, the hypothalamus starts to secrete GnRH in pulses, sometimes more and sometimes less, and pituitary FSH and LH make the ovarian follicles develop.
One example is thyroid hyperplasia, an enlargement of the thyroid gland caused by an abnormal rapid growth of the epithelial cells lining the follicles.
A different cause is a hyper functioning thyroid adenoma where the follicular cells start growing uncontrollably, forming a benign tumor that makes excess thyroid hormones.
Other activated B-cells go to the center of a primary follicle in the lymph node and they differentiate into B-cells called centroblasts and start to proliferate or divide.
With polycystic ovary syndrome, the ovarian follicles secrete too much testosterone, causing hirsutism, or excessive hair growth on the chin and upper lip, chest, and back.